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The Effects of Single Nucleotide Polymorphisms in Cancer RNAi Therapies

SIMPLE SUMMARY: Despite the recent progress in RNAi delivery of siRNA-based therapeutics for cancer therapy, the presence of single nucleotide polymorphisms (SNPs) in the general population could dramatically reduce the effectiveness of RNAi therapy. Their ubiquitous presence can also lead to unpred...

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Publicat a:Cancers (Basel)
Autors principals: Gebert, Magdalena, Jaśkiewicz, Maciej, Moszyńska, Adrianna, Collawn, James F., Bartoszewski, Rafał
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694039/
https://ncbi.nlm.nih.gov/pubmed/33113880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113119
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