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The Effects of Single Nucleotide Polymorphisms in Cancer RNAi Therapies

SIMPLE SUMMARY: Despite the recent progress in RNAi delivery of siRNA-based therapeutics for cancer therapy, the presence of single nucleotide polymorphisms (SNPs) in the general population could dramatically reduce the effectiveness of RNAi therapy. Their ubiquitous presence can also lead to unpred...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Gebert, Magdalena, Jaśkiewicz, Maciej, Moszyńska, Adrianna, Collawn, James F., Bartoszewski, Rafał
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694039/
https://ncbi.nlm.nih.gov/pubmed/33113880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113119
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