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Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy

The synucleinopathy underlying multiple system atrophy (MSA) is characterized by the presence of abundant amyloid inclusions containing fibrillar α-synuclein (α-syn) aggregates in the brains of the patients and is associated with an extensive neurodegeneration. In contrast to Parkinson’s disease (PD...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Laferrière, Florent, He, Xin, Zinghirino, Federica, Doudnikoff, Evelyne, Faggiani, Emilie, Meissner, Wassilios G., Bezard, Erwan, De Giorgi, Francesca, Ichas, François
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693764/
https://ncbi.nlm.nih.gov/pubmed/33138150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112371
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