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Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy

The synucleinopathy underlying multiple system atrophy (MSA) is characterized by the presence of abundant amyloid inclusions containing fibrillar α-synuclein (α-syn) aggregates in the brains of the patients and is associated with an extensive neurodegeneration. In contrast to Parkinson’s disease (PD...

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Библиографические подробности
Опубликовано в: :Cells
Главные авторы: Laferrière, Florent, He, Xin, Zinghirino, Federica, Doudnikoff, Evelyne, Faggiani, Emilie, Meissner, Wassilios G., Bezard, Erwan, De Giorgi, Francesca, Ichas, François
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693764/
https://ncbi.nlm.nih.gov/pubmed/33138150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112371
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