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Targeting α-Synuclein for PD Therapeutics: A Pursuit on All Fronts

Parkinson’s Disease (PD) is characterized both by the loss of dopaminergic neurons in the substantia nigra and the presence of cytoplasmic inclusions called Lewy Bodies. These Lewy Bodies contain the aggregated α-synuclein (α-syn) protein, which has been shown to be able to propagate from cell to ce...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Teil, Margaux, Arotcarena, Marie-Laure, Faggiani, Emilie, Laferriere, Florent, Bezard, Erwan, Dehay, Benjamin
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7175302/
https://ncbi.nlm.nih.gov/pubmed/32138193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10030391
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