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Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death

Neurodegenerative diseases are (i) characterized by a selective neuronal vulnerability to degeneration in specific brain regions; and (ii) likely to be caused by disease-specific protein misfolding. Parkinson’s disease (PD) is characterized by the presence of intraneuronal proteinacious cytoplasmic...

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Detalhes bibliográficos
Main Authors: Bourdenx, Mathieu, Bezard, Erwan, Dehay, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132369/
https://ncbi.nlm.nih.gov/pubmed/25177278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2014.00083
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