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Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases
Lysosomal impairment causes lysosomal storage disorders (LSD) and is involved in pathogenesis of neurodegenerative diseases, notably Parkinson disease (PD). Strategies enhancing or restoring lysosomal-mediated degradation thus appear as tantalizing disease-modifying therapeutics. Here we demonstrate...
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| Publicado no: | Autophagy |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835967/ https://ncbi.nlm.nih.gov/pubmed/26761717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1136769 |
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