Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases

Lysosomal impairment causes lysosomal storage disorders (LSD) and is involved in pathogenesis of neurodegenerative diseases, notably Parkinson disease (PD). Strategies enhancing or restoring lysosomal-mediated degradation thus appear as tantalizing disease-modifying therapeutics. Here we demonstrate...

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Podrobná bibliografie
Vydáno v:Autophagy
Hlavní autoři: Bourdenx, Mathieu, Daniel, Jonathan, Genin, Emilie, Soria, Federico N., Blanchard-Desce, Mireille, Bezard, Erwan, Dehay, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Translational Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835967/
https://ncbi.nlm.nih.gov/pubmed/26761717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1136769
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