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Systemic gene delivery to the central nervous system using Adeno-associated virus

Adeno-associated virus (AAV)-mediated gene delivery has emerged as an effective and safe tool for both preclinical and clinical studies of neurological disorders. The recent discovery that several serotypes are able to cross the blood–brain barrier when administered systemically has been a real brea...

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Hlavní autoři: Bourdenx, Mathieu, Dutheil, Nathalie, Bezard, Erwan, Dehay, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040820/
https://ncbi.nlm.nih.gov/pubmed/24917785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00050
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