Systemic gene delivery to the central nervous system using Adeno-associated virus

Adeno-associated virus (AAV)-mediated gene delivery has emerged as an effective and safe tool for both preclinical and clinical studies of neurological disorders. The recent discovery that several serotypes are able to cross the blood–brain barrier when administered systemically has been a real brea...

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Bibliographic Details
Main Authors: Bourdenx, Mathieu, Dutheil, Nathalie, Bezard, Erwan, Dehay, Benjamin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040820/
https://ncbi.nlm.nih.gov/pubmed/24917785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00050
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