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Adeno-associated virus-mediated delivery of CRISPR-Cas9 for genome editing in the central nervous system
The emergence of CRISPR-Cas9 as a powerful genome editing tool has led to several studies exploring its potential to treat neurological disorders. Cas9 and its sgRNA can be readily engineered to target any gene and can be multiplexed to target several genes at once. Furthermore, the use of adeno-ass...
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| Publicado no: | Curr Opin Biomed Eng |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8153090/ https://ncbi.nlm.nih.gov/pubmed/34046535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cobme.2018.08.003 |
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