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Virus-Like Particle Mediated CRISPR/Cas9 Delivery for Efficient and Safe Genome Editing

The discovery of designer nucleases has made genome editing much more efficient than before. The designer nucleases have been widely used for mechanistic studies, animal model generation and gene therapy development. However, potential off-targets and host immune responses are issues still need to b...

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Detalhes bibliográficos
Publicado no:Life (Basel)
Main Authors: Lyu, Pin, Wang, Luxi, Lu, Baisong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766694/
https://ncbi.nlm.nih.gov/pubmed/33371215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life10120366
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