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Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells

The CRISPR/Cas9 system is a highly effective tool for genome editing. Key to robust genome editing is the efficient delivery of the CRISPR/Cas9 machinery. Viral delivery systems are efficient vehicles for the transduction of foreign genes but commonly used viral vectors suffer from a limited capacit...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Hindriksen, Sanne, Bramer, Arne J., Truong, My Anh, Vromans, Martijn J. M., Post, Jasmin B., Verlaan-Klink, Ingrid, Snippert, Hugo J., Lens, Susanne M. A., Hadders, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480884/
https://ncbi.nlm.nih.gov/pubmed/28640891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179514
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