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Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis

Aurora B kinase is essential for faithful chromosome segregation during mitosis. During (pro)metaphase, Aurora B is concentrated at the inner centromere by the kinases Haspin and Bub1. However, how Haspin and Bub1 collaborate to control Aurora B activity at centromeres remains unclear. Here, we show...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Hadders, Michael A., Hindriksen, Sanne, Truong, My Anh, Mhaskar, Aditya N., Wopken, J. Pepijn, Vromans, Martijn J.M., Lens, Susanne M.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054988/
https://ncbi.nlm.nih.gov/pubmed/32027339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907087
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