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Rational Design of a DNA‐Scaffolded High‐Affinity Binder for Langerin
Binders of langerin could target vaccines to Langerhans cells for improved therapeutic effect. Since langerin has low affinity for monovalent glycan ligands, highly multivalent presentation has previously been key for targeting. Aiming to reduce the amount of ligand required, we rationally designed...
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| 出版年: | Angew Chem Int Ed Engl |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7693190/ https://ncbi.nlm.nih.gov/pubmed/32749019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202006880 |
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