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Multivalent scaffolds for affinity maturation of small molecule cell surface-binders and their application to prostate tumor targeting
Adamantane scaffolds for affinity maturation of prostate cancer specific ligands of low molecular mass are described. These scaffolds are modular and can be used for conjugation of up to three ligands and an additional effector molecule by standard peptide coupling techniques. The potential of the s...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628416/ https://ncbi.nlm.nih.gov/pubmed/19108655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm801033c |
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