Tumors establish resistance to immunotherapy by regulating T(reg) recruitment via CCR4

BACKGROUND: Checkpoint inhibitors (CPIs) such as anti-PD(L)-1 and anti-CTLA-4 antibodies have resulted in unprecedented rates of antitumor responses and extension of survival of patients with a variety of cancers. But some patients fail to respond or initially respond but later relapse as they devel...

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Detalles Bibliográficos
Publicado en:J Immunother Cancer
Main Authors: Marshall, Lisa A, Marubayashi, Sachie, Jorapur, Aparna, Jacobson, Scott, Zibinsky, Mikhail, Robles, Omar, Hu, Dennis Xiaozhou, Jackson, Jeffrey J, Pookot, Deepa, Sanchez, Jerick, Brovarney, Martin, Wadsworth, Angela, Chian, David, Wustrow, David, Kassner, Paul D, Cutler, Gene, Wong, Brian, Brockstedt, Dirk G, Talay, Oezcan
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692993/
https://ncbi.nlm.nih.gov/pubmed/33243932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000764
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