Tumors establish resistance to immunotherapy by regulating T(reg) recruitment via CCR4

BACKGROUND: Checkpoint inhibitors (CPIs) such as anti-PD(L)-1 and anti-CTLA-4 antibodies have resulted in unprecedented rates of antitumor responses and extension of survival of patients with a variety of cancers. But some patients fail to respond or initially respond but later relapse as they devel...

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Opis bibliograficzny
Wydane w:J Immunother Cancer
Główni autorzy: Marshall, Lisa A, Marubayashi, Sachie, Jorapur, Aparna, Jacobson, Scott, Zibinsky, Mikhail, Robles, Omar, Hu, Dennis Xiaozhou, Jackson, Jeffrey J, Pookot, Deepa, Sanchez, Jerick, Brovarney, Martin, Wadsworth, Angela, Chian, David, Wustrow, David, Kassner, Paul D, Cutler, Gene, Wong, Brian, Brockstedt, Dirk G, Talay, Oezcan
Format: Artigo
Język:Inglês
Wydane: BMJ Publishing Group 2020
Hasła przedmiotowe:
Basic Tumor Immunology
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692993/
https://ncbi.nlm.nih.gov/pubmed/33243932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000764
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