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In vitro Differentiation of Thymic T(reg )Cell Progenitors to Mature Thymic T(reg )Cells
Thymic T(reg) cell differentiation occurs via a two-step process. Step one generates T(reg) cell progenitors (T(reg)P) and is driven by strong TCR interactions with antigens presented in the thymus. Step two is initiated by activation of STAT5 via IL-2, or IL-15, leading to mature T(reg) cells capab...
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| 出版年: | Bio Protoc |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Bio-Protocol
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7854127/ https://ncbi.nlm.nih.gov/pubmed/33654840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3335 |
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