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In vitro Differentiation of Thymic T(reg )Cell Progenitors to Mature Thymic T(reg )Cells

Thymic T(reg) cell differentiation occurs via a two-step process. Step one generates T(reg) cell progenitors (T(reg)P) and is driven by strong TCR interactions with antigens presented in the thymus. Step two is initiated by activation of STAT5 via IL-2, or IL-15, leading to mature T(reg) cells capab...

詳細記述

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書誌詳細
出版年:Bio Protoc
主要な著者: Owen, David L., Farrar, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: Bio-Protocol 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854127/
https://ncbi.nlm.nih.gov/pubmed/33654840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3335
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