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In vitro Differentiation of Thymic T(reg )Cell Progenitors to Mature Thymic T(reg )Cells
Thymic T(reg) cell differentiation occurs via a two-step process. Step one generates T(reg) cell progenitors (T(reg)P) and is driven by strong TCR interactions with antigens presented in the thymus. Step two is initiated by activation of STAT5 via IL-2, or IL-15, leading to mature T(reg) cells capab...
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| Publicat a: | Bio Protoc |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Bio-Protocol
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7854127/ https://ncbi.nlm.nih.gov/pubmed/33654840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3335 |
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