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Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feeding

BACKGROUND: Circulating high-mobility group box 1 (HMGB1) plays important roles in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Intracellular HMGB1 is critical for the biology of hepatocytes. However, the intracellular role of HMGB1 in hepatocellular steatosis is unknown. Therefore,...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Med
Egile Nagusiak: Lin, Minjie, Long, Jungke, Li, Wenbo, Yang, Chenxuan, Loughran, Patricia, O’Doherty, Robert, Billiar, Timothy R., Deng, Meihong, Scott, Melanie J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687718/
https://ncbi.nlm.nih.gov/pubmed/33238880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-020-00227-6
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