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High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli

Understanding the constraints that shape the evolution of antibiotic resistance is critical for predicting and controlling drug resistance. Despite its importance, however, a systematic investigation of evolutionary constraints is lacking. Here, we perform a high-throughput laboratory evolution of E...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Maeda, Tomoya, Iwasawa, Junichiro, Kotani, Hazuki, Sakata, Natsue, Kawada, Masako, Horinouchi, Takaaki, Sakai, Aki, Tanabe, Kumi, Furusawa, Chikara
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686311/
https://ncbi.nlm.nih.gov/pubmed/33235191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19713-w
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