High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli

Understanding the constraints that shape the evolution of antibiotic resistance is critical for predicting and controlling drug resistance. Despite its importance, however, a systematic investigation of evolutionary constraints is lacking. Here, we perform a high-throughput laboratory evolution of E...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Maeda, Tomoya, Iwasawa, Junichiro, Kotani, Hazuki, Sakata, Natsue, Kawada, Masako, Horinouchi, Takaaki, Sakai, Aki, Tanabe, Kumi, Furusawa, Chikara
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686311/
https://ncbi.nlm.nih.gov/pubmed/33235191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19713-w
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