The COX-2-derived PGE(2) autocrine contributes to bradykinin-induced matrix metalloproteinase-9 expression and astrocytic migration via STAT3 signaling

BACKGROUND: The matrix metalloproteinase-9 (MMP-9) is up-regulated by several proinflammatory mediators in the central nervous system (CNS) diseases. Increasing reports show that MMP-9 expression is an inflammatory biomarker of several CNS disorders, including the CNS inflammation and neurodegenerat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Commun Signal
Hauptverfasser: Lee, Tsong-Hai, Liu, Pei-Shan, Tsai, Ming-Ming, Chen, Jiun-Liang, Wang, Su-Jane, Hsieh, Hsi-Lung
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685582/
https://ncbi.nlm.nih.gov/pubmed/33228717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00680-0
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge