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PAR1-dependent COX-2/PGE(2) production contributes to cell proliferation via EP(2) receptors in primary human cardiomyocytes
BACKGROUND AND PURPOSE: Different protease-activated receptors (PARs) activated by thrombin are involved in cardiovascular disease, via up-regulation of inflammatory proteins including COX-2. However, the mechanisms underlying thrombin-regulated COX-2 expression in human cardiomyocytes remain unclea...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4209155/ https://ncbi.nlm.nih.gov/pubmed/24902855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12794 |
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