PAR1-dependent COX-2/PGE(2) production contributes to cell proliferation via EP(2) receptors in primary human cardiomyocytes

BACKGROUND AND PURPOSE: Different protease-activated receptors (PARs) activated by thrombin are involved in cardiovascular disease, via up-regulation of inflammatory proteins including COX-2. However, the mechanisms underlying thrombin-regulated COX-2 expression in human cardiomyocytes remain unclea...

Full description

Saved in:
Bibliographic Details
Main Authors: Chien, Peter Tzu-Yu, Hsieh, Hsi-Lung, Chi, Pei-Ling, Yang, Chuen-Mao
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209155/
https://ncbi.nlm.nih.gov/pubmed/24902855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12794
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items