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NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes

BACKGROUND: Matrix metalloproteinase-9 (MMP-9) plays a crucial role in pathological processes of brain inflammation, injury, and neurodegeneration. Moreover, bradykinin (BK) induces the expression of several inflammatory proteins in brain astrocytes. Recent studies have suggested that increased oxid...

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Main Authors: Lin, Chih-Chung, Hsieh, Hsi-Lung, Shih, Ruey-Horng, Chi, Pei-Ling, Cheng, Shin-Ei, Chen, Jin-Chung, Yang, Chuen-Mao
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518199/
https://ncbi.nlm.nih.gov/pubmed/23176293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-10-35
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