NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes

BACKGROUND: Matrix metalloproteinase-9 (MMP-9) plays a crucial role in pathological processes of brain inflammation, injury, and neurodegeneration. Moreover, bradykinin (BK) induces the expression of several inflammatory proteins in brain astrocytes. Recent studies have suggested that increased oxid...

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Detalhes bibliográficos
Main Authors: Lin, Chih-Chung, Hsieh, Hsi-Lung, Shih, Ruey-Horng, Chi, Pei-Ling, Cheng, Shin-Ei, Chen, Jin-Chung, Yang, Chuen-Mao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518199/
https://ncbi.nlm.nih.gov/pubmed/23176293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-10-35
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