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An engineered receptor-binding domain improves the immunogenicity of multivalent SARS-CoV-2 vaccines
The SARS-coronavirus 2 (SARS-CoV-2) spike (S) protein mediates viral entry into cells expressing the angiotensin-converting enzyme 2 (ACE2). The S protein engages ACE2 through its receptor-binding domain (RBD), an independently folded 197-amino acid fragment of the 1273-amino acid S-protein protomer...
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| izdano v: | bioRxiv |
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| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7685318/ https://ncbi.nlm.nih.gov/pubmed/33236008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.11.18.388934 |
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