An engineered receptor-binding domain improves the immunogenicity of multivalent SARS-CoV-2 vaccines

The SARS-coronavirus 2 (SARS-CoV-2) spike (S) protein mediates viral entry into cells expressing the angiotensin-converting enzyme 2 (ACE2). The S protein engages ACE2 through its receptor-binding domain (RBD), an independently folded 197-amino acid fragment of the 1273-amino acid S-protein protomer...

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Detaylı Bibliyografya
Yayımlandı:bioRxiv
Asıl Yazarlar: Quinlan, Brian D., He, Wenhui, Mou, Huihui, Zhang, Lizhou, Guo, Yan, Chang, Jing, Peng, Shoujiao, Ojha, Amrita, Tavora, Rubens, Parcells, Mark S., Luo, Guangxiang, Li, Wenhui, Zhong, Guocai, Choe, Hyeryun, Farzan, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685318/
https://ncbi.nlm.nih.gov/pubmed/33236008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.11.18.388934
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