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The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity
SARS coronavirus 2 (SARS-CoV-2) isolates encoding a D614G mutation in the viral spike (S) protein predominate over time in locales where it is found, implying that this change enhances viral transmission. We therefore compared the functional properties of the S proteins with aspartic acid (S(D614))...
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| 出版年: | bioRxiv |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7310631/ https://ncbi.nlm.nih.gov/pubmed/32587973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.12.148726 |
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