Autoantibodies against the prion protein in individuals with PRNP mutations

OBJECTIVE: To determine whether naturally occurring autoantibodies against the prion protein are present in individuals with genetic prion disease mutations and controls, and if so, whether they are protective against prion disease. METHODS: In this case–control study, we collected 124 blood samples...

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Bibliografski detalji
Izdano u:Neurology
Glavni autori: Frontzek, Karl, Carta, Manfredi, Losa, Marco, Epskamp, Mirka, Meisl, Georg, Anane, Alice, Brandel, Jean-Philippe, Camenisch, Ulrike, Castilla, Joaquín, Haïk, Stéphane, Knowles, Tuomas, Lindner, Ewald, Lutterotti, Andreas, Minikel, Eric Vallabh, Roiter, Ignazio, Safar, Jiri G., Sanchez-Valle, Raquel, Žáková, Dana, Hornemann, Simone, Aguzzi, Adriano
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2020
Teme:
Null Hypothesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682844/
https://ncbi.nlm.nih.gov/pubmed/32098855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000009183
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