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Strictly co-isogenic C57BL/6J-Prnp(−/−) mice: A rigorous resource for prion science
Although its involvement in prion replication and neurotoxicity during transmissible spongiform encephalopathies is undisputed, the physiological role of the cellular prion protein (PrP(C)) remains enigmatic. A plethora of functions have been ascribed to PrP(C) based on phenotypes of Prnp(−/−) mice....
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813672/ https://ncbi.nlm.nih.gov/pubmed/26926995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151610 |
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