Autoantibodies against the prion protein in individuals with PRNP mutations

OBJECTIVE: To determine whether naturally occurring autoantibodies against the prion protein are present in individuals with genetic prion disease mutations and controls, and if so, whether they are protective against prion disease. METHODS: In this case–control study, we collected 124 blood samples...

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Detalles Bibliográficos
Publicado en:Neurology
Main Authors: Frontzek, Karl, Carta, Manfredi, Losa, Marco, Epskamp, Mirka, Meisl, Georg, Anane, Alice, Brandel, Jean-Philippe, Camenisch, Ulrike, Castilla, Joaquín, Haïk, Stéphane, Knowles, Tuomas, Lindner, Ewald, Lutterotti, Andreas, Minikel, Eric Vallabh, Roiter, Ignazio, Safar, Jiri G., Sanchez-Valle, Raquel, Žáková, Dana, Hornemann, Simone, Aguzzi, Adriano
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2020
Assuntos:
Null Hypothesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682844/
https://ncbi.nlm.nih.gov/pubmed/32098855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000009183
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