Rapamycin‐mediated mouse lifespan extension: Late‐life dosage regimes with sex‐specific effects

To see if variations in timing of rapamycin (Rapa), administered to middle aged mice starting at 20 months, would lead to different survival outcomes, we compared three dosing regimens. Initiation of Rapa at 42 ppm increased survival significantly in both male and female mice. Exposure to Rapa for a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: Strong, Randy, Miller, Richard A., Bogue, Molly, Fernandez, Elizabeth, Javors, Martin A., Libert, Sergiy, Marinez, Paul Anthony, Murphy, Michael P., Musi, Nicolas, Nelson, James F., Petrascheck, Michael, Reifsnyder, Peter, Richardson, Arlan, Salmon, Adam B., Macchiarini, Francesca, Harrison, David E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681050/
https://ncbi.nlm.nih.gov/pubmed/33145977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13269
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak