Structure-Activity Relationships for a Series of (Bis(4-fluorophenyl)methyl)sulfinylethyl-aminopiperidines and -piperidine amines at the Dopamine Transporter: Bioisosteric Replacement of the Piperazine Improves Metabolic Stability

Despite considerable efforts to develop medications to treat psychostimulant use disorders, none have proven effective, leaving an underserved patient population and unanswered questions as to what mechanism(s) of action should be targeted for developing pharmacotherapies. Atypical dopamine transpor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Eur J Med Chem
Egile Nagusiak: Giancola, JoLynn B., Bonifazi, Alessandro, Cao, Jianjing, Ku, Therese, Haraczy, Alexandra J., Lam, Jenny, Rais, Rana, Coggiano, Mark A., Tanda, Gianluigi, Newman, Amy Hauck
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680422/
https://ncbi.nlm.nih.gov/pubmed/32947229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112674
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