Dual DAT/σ1 receptor ligands based on 3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-3-phenylpropan-1-ol

[Image: see text] Ester analogues of (±)3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-3-phenylpropan-1-ol were synthesized and evaluated for binding at DAT, SERT, NET and σ1 receptors, and compared to GBR 12909 and several known σ1 receptor ligands. Most of these compounds demonstrated hi...

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Bibliographic Details
Main Authors:	Cao, Jianjing, Kopajtic, Theresa, Katz, Jonathan L., Newman, Amy Hauck
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3393102/ https://ncbi.nlm.nih.gov/pubmed/18774292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.08.065
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Dual DAT/σ1 receptor ligands based on 3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-3-phenylpropan-1-ol

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