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Modular affinity-labeling of the cytosine demethylation base elements in DNA

5-methylcytosine is the most studied DNA epigenetic modification, having been linked to diverse biological processes and disease states. The elucidation of cytosine demethylation has drawn added attention the three additional intermediate modifications involved in that pathway—5-hydroxymethylcytosin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Fanny, Zahid, Osama K., Ghanty, Uday, Kohli, Rahul M., Hall, Adam R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679407/
https://ncbi.nlm.nih.gov/pubmed/33219273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76544-x
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