Solid-state nanopore analysis of diverse DNA base modifications using a modular enzymatic labeling process

Many regulated epigenetic elements and base lesions found in genomic DNA can both directly impact gene expression and play a role in disease processes. However, due to their non-canonical nature, they are challenging to assess with conventional technologies. Here, we present a new approach for the t...

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Veröffentlicht in:Nano Lett
Hauptverfasser: Wang, Fanny, Zahid, Osama K., Swain, Brandi E., Parsonage, Derek, Hollis, Thomas, Harvey, Scott, Perrino, Fred W., Kohli, Rahul M., Taylor, Ethan W., Hall, Adam R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704975/
https://ncbi.nlm.nih.gov/pubmed/28967259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.7b03911
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