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Quantifying mammalian genomic DNA hydroxymethylcytosine content using solid-state nanopores
5-hydroxymethylcytosine (5 hmC), the oxidized form of 5-methylcytosine (5 mC), is a base modification with emerging importance in biology and disease. However, like most epigenetic elements, it is transparent to many conventional genetic techniques and is thus challenging to probe. Here, we report a...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935868/ https://ncbi.nlm.nih.gov/pubmed/27383905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29565 |
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