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Quantifying mammalian genomic DNA hydroxymethylcytosine content using solid-state nanopores

5-hydroxymethylcytosine (5 hmC), the oxidized form of 5-methylcytosine (5 mC), is a base modification with emerging importance in biology and disease. However, like most epigenetic elements, it is transparent to many conventional genetic techniques and is thus challenging to probe. Here, we report a...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Zahid, Osama K., Zhao, Boxuan Simen, He, Chuan, Hall, Adam R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935868/
https://ncbi.nlm.nih.gov/pubmed/27383905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29565
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