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AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation

AID/APOBEC family cytosine deaminases, known to function in diverse cellular processes from antibody diversification to mRNA editing, have also been implicated in DNA demethylation, an important process for transcriptional activation. While oxidation-dependent pathways for demethylation have been de...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nabel, Christopher S., Jia, Huijue, Ye, Yu, Shen, Li, Goldschmidt, Hana L., Stivers, James T., Zhang, Yi, Kohli, Rahul M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427411/
https://ncbi.nlm.nih.gov/pubmed/22772155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1042
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