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APOBEC3A efficiently deaminates methylated, but not TET-oxidized, cytosine bases in DNA
AID/APOBEC family enzymes are best known for deaminating cytosine bases to uracil in single-stranded DNA, with characteristic sequence preferences that can produce mutational signatures in targets such as retroviral and cancer cell genomes. These deaminases have also been proposed to function in DNA...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570014/ https://ncbi.nlm.nih.gov/pubmed/28472485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx345 |
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