Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X

We developed cis-X, a computational method for discovery of regulatory noncoding variants in cancer by integrating whole genome and transcriptome sequencing data from a single cancer sample. cis-X first finds aberrantly cis-activated genes that exhibit allele-specific expression accompanied by an el...

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書誌詳細
出版年:Nat Genet
主要な著者: Liu, Yu, Li, Chunliang, Shen, Shuhong, Chen, Xiaolong, Szlachta, Karol, Edmonson, Michael N., Shao, Ying, Ma, Xiaotu, Hyle, Judith, Wright, Shaela, Ju, Bensheng, Rusch, Michael C., Liu, Yanling, Li, Benshang, Macias, Michael, Tian, Liqing, Easton, John, Qian, Maoxiang, Yang, Jun J., Hu, Shaoyan, Look, A. Thomas, Zhang, Jinghui
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679232/
https://ncbi.nlm.nih.gov/pubmed/32632335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0659-5
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