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Acute depletion of CTCF directly affects MYC regulation through loss of enhancer–promoter looping

Numerous pieces of evidence support the complex, 3D spatial organization of the genome dictates gene expression. CTCF is essential to define topologically associated domain boundaries and to facilitate the formation of insulated chromatin loop structures. To understand CTCF’s direct role in global t...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Hyle, Judith, Zhang, Yang, Wright, Shaela, Xu, Beisi, Shao, Ying, Easton, John, Tian, Liqing, Feng, Ruopeng, Xu, Peng, Li, Chunliang
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648894/
https://ncbi.nlm.nih.gov/pubmed/31127282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz462
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