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Acute depletion of CTCF directly affects MYC regulation through loss of enhancer–promoter looping
Numerous pieces of evidence support the complex, 3D spatial organization of the genome dictates gene expression. CTCF is essential to define topologically associated domain boundaries and to facilitate the formation of insulated chromatin loop structures. To understand CTCF’s direct role in global t...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6648894/ https://ncbi.nlm.nih.gov/pubmed/31127282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz462 |
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