Carregant...
A cis-element within the ARF locus mediates repression of p16(INK4A) expression via long-range chromatin interactions
Loss of function of CDKN2A/B, also known as INK4/ARF [encoding p16(INK4A), p15(INK4B), and p14(ARF) (mouse p19(Arf))], confers susceptibility to cancers, whereas its up-regulation during organismal aging provokes cellular senescence and tissue degenerative disorders. To better understand the transcr...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2019
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6936709/ https://ncbi.nlm.nih.gov/pubmed/31818950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909720116 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|