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Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs

Adaptive designs for clinical trials permit alterations to a study in response to accumulating data in order to make trials more flexible, ethical, and efficient. These benefits are achieved while preserving the integrity and validity of the trial, through the pre-specification and proper adjustment...

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Dades bibliogràfiques
Publicat a:BMC Med
Autors principals: Burnett, Thomas, Mozgunov, Pavel, Pallmann, Philip, Villar, Sofia S., Wheeler, Graham M., Jaki, Thomas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677786/
https://ncbi.nlm.nih.gov/pubmed/33208155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-020-01808-2
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