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Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs
Abstract Adaptive designs for clinical trials permit alterations to a study in response to accumulating data in order to make trials more flexible, ethical, and efficient. These benefits are achieved while preserving the integrity and validity of the trial, through the pre-specification and proper a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-11-01
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| Colecção: | BMC Medicine |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12916-020-01808-2 |
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