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A Bayesian adaptive design for clinical trials in rare diseases

Development of treatments for rare diseases is challenging due to the limited number of patients available for participation. Learning about treatment effectiveness with a view to treat patients in the larger outside population, as in the traditional fixed randomised design, may not be a plausible g...

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Detalhes bibliográficos
Publicado no:Comput Stat Data Anal
Main Authors: Williamson, S. Faye, Jacko, Peter, Villar, Sofía S., Jaki, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473477/
https://ncbi.nlm.nih.gov/pubmed/28630525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2016.09.006
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