Medulloblastoma cells resemble neuronal progenitors in their differentiation

Medulloblastoma (MB) often originate from cerebellar granule neuron precursors (GNPs). We recently found that medulloblastoma cells undergo differentiation as GNPs. Differentiated MB cells have permanently lost their proliferative capacity and tumorigenicity. The differentiation of MB cells is drive...

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Udgivet i:Mol Cell Oncol
Main Authors: Guo, Duancheng, Qu, Yanghui, Yang, Yijun, Yang, Zeng-Jie
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671073/
https://ncbi.nlm.nih.gov/pubmed/33235914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1810514
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