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OTX2 Represses Myogenic and Neuronal Differentiation in Medulloblastoma Cells
The brain development transcription factor OTX2 is overexpressed and/or genomically amplified in most medulloblastomas, but the mechanistic basis for its contributions in this setting are not understood. In this study we identified OTX2 as a transcriptional repressor and a gatekeeper of myogenic and...
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| Pubblicato in: | Cancer Res |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861240/ https://ncbi.nlm.nih.gov/pubmed/22986744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0614 |
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