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OTX2 Represses Myogenic and Neuronal Differentiation in Medulloblastoma Cells

The brain development transcription factor OTX2 is overexpressed and/or genomically amplified in most medulloblastomas, but the mechanistic basis for its contributions in this setting are not understood. In this study we identified OTX2 as a transcriptional repressor and a gatekeeper of myogenic and...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Bai, Ren-Yuan, Staedtke, Verena, Lidov, Hart G., Eberhart, Charles G., Riggins, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861240/
https://ncbi.nlm.nih.gov/pubmed/22986744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0614
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