A carregar...
Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling
Smoothened (SMO), a class-Frizzled G protein-coupled receptor (class-F GPCR), transduces the Hedgehog signal across cell membrane. Sterols can bind to its extracellular cysteine rich domain (CRD) and to several sites in the 7 transmembrane helices (7-TMs) of SMO. However, the mechanism how sterols r...
Na minha lista:
| Publicado no: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7669734/ https://ncbi.nlm.nih.gov/pubmed/32929279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0646-2 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|