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Mechanistic insights into the generation and transduction of Hedgehog Signaling
Cell differentiation and proliferation require Hedgehog (HH) signaling, and aberrant HH signaling causes birth defects or cancers. In this signaling pathway, the N-terminally palmitoylated and C-terminally cholesterylated HH ligand is secreted into the extracellular space with help of Dispatched-1 (...
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| Pubblicato in: | Trends Biochem Sci |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7174405/ https://ncbi.nlm.nih.gov/pubmed/32311334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2020.01.006 |
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